What is Upneeq?

Upneeq is the only FDA-approved once-daily prescription eyedrop for acquired ptosis (low-lying lids) that lifts your upper eyelids to open your eyes.

Are low-lying eyelids making your eyes look a little tired?
You may have acquired ptosis.

Acquired ptosis (low-lying lids) is a common medical condition that:

  • Can develop later in life
  • Affects adults of all ages, but occurs more often with increased age
  • Usually occurs when the muscles in the eyelid stretch and weaken, causing the upper eyelid to droop
  • May be caused by other issues, such as cataract surgery, contact lens wear, or an underlying medical condition. It could also be a sign of a more serious medical condition.

Can you recognize acquired ptosis (low-lying lids)?

levels of severity of ptosis from normal to severe

Millions of people who have acquired ptosis may not even be aware of it

  • Millions of people over the age of 40 may have acquired ptosis
  • But only 15% have been diagnosed, and even fewer have received any treatment*

*Estimate of prevalence was calculated using both U.S. Census data and a published study by Sridharan et al. (1995). The Sridharan study observed a prevalence rate of 11.5% (n=400), which was then applied to the US Census’ projected 2020 population of Americans aged 50+ years.

What can Upneeq do for you?

Lifts eyelid(s) quickly 

  • Most patients in clinical trials had a lift in their eyelids in as little as 2 hours
    • 84% of patients had some form of improvement
    • 74% of patients had more than a 50% improvement
  • In one study, some patients saw a lift in their eyelids as fast as 5 minutes after the first dose

Significantly improves upper field of vision

  • In clinical trials, Upneeq helped patients with acquired ptosis see more—on the first day of treatment!
    • 87.8% of patients had some form of improvement
    • 40.8% of patients had at least a 50% improvement on Day 14 (2 hours after applying Upneeq)

Examples of positive results after the first dose of Upneeq

Upneeq before and after patient images | Plastic Surgery Specialists

Actual patient images courtesy of Dr. Robert Schwarcz and Dr. Raymond Douglas. Individual results may vary. The average lift seen in clinical trials was 1 mm.

To learn if Upneeq is right for you, start with a consultation with one of our doctors at our main office in Annapolis or one of our satellite offices in Easton or Prince Frederick to determine if you are a good candidate for Upneeq.

 

Acquired ptosis can lead to vision impairment

  • Low-lying eyelid(s) can affect eyesight by not only blocking your vision, but also by reducing field of vision, which may interfere with day-to-day functions such as:
    • Reading
    • Driving
    • Computer use
    • Looking up without the need to tilt your head back

Do you have low-lying lids?

If you’re considering Upneeq, your next step should be a consultation with one of our board-certified plastic surgeons.

IMPORTANT SAFETY INFORMATION

What is UPNEEQ?

UPNEEQ® (oxymetazoline hydrochloride ophthalmic solution), 0.1% is a prescription eyedrop used to treat acquired blepharoptosis (low-lying lids) in adults.

What warnings and precautions are associated with UPNEEQ?

  • Low-lying lids may be related to conditions such as stroke and/or brain aneurysm, Horner syndrome, myasthenia gravis, loss of the ability to move eye muscles, eye infection and eye tumors. Tell your doctor if you have any of these conditions.
  • UPNEEQ is a type of medication that may affect your blood pressure. If you have heart disease, uncontrolled high or low blood pressure, or feel faint at rest or when quickly standing up, you should call your doctor if your symptoms get worse.
  • Patients with reduced blood flow to the brain or heart, or patients who experience eye or mouth dryness due to an immune system disorder (Sjögren’s syndrome), should use care when taking UPNEEQ. Call your doctor immediately if you feel your symptoms may be getting worse.
  • UPNEEQ may increase the risk of eye pressure due to fluid buildup (angle-closure glaucoma) in patients with untreated narrow-angle glaucoma. Call your doctor immediately if you feel increased pressure in your eye after using UPNEEQ.
  • Do not let the tip of the UPNEEQ vial touch your eye or any other surface. This can help prevent eye injury or contamination. Each UPNEEQ vial is for one-time use and should be discarded after being used.

What are the most common side effects of UPNEEQ?

The most common adverse reactions with UPNEEQ (occurring in 1-5% of patients) were eye inflammation, eye redness, dry eye, blurred vision, eye pain at time of use, eye irritation, and headache.

What should my doctor know about before prescribing me UPNEEQ?

  • Your doctor should review your full medical history before prescribing UPNEEQ.
  • UPNEEQ belongs to a class of medication (alpha-adrenergic agonists) that may affect your blood pressure. Use UPNEEQ carefully if you currently take an alpha-adrenergic agonist medication to treat heart disease or an enlarged prostate. Patients taking beta-blockers, or other medications to treat hypertension or an abnormal heartbeat, should also be careful when using UPNEEQ.
  • Patients who use a certain class of antidepressant medication (monoamine oxidase inhibitors) should also be careful when using UPNEEQ, as it may affect the way your body absorbs the medication.